Abstract:

Krukenburg tumor refers to an ovarian malignancy that metastasizes from a primary site, and its incidence is relatively low. Pregnancy complicated by Krukenberg tumor is even rarer in clinical practice, often associated with a poor prognosis. Most patients exhibit nonspecific early clinical symptoms, which are easily masked by physiological and hormonal changes during pregnancy, making early diagnosis challenging, leading to delayed diagnosis and missed optimal treatment timing. To date, there is no consensus on the diagnosis and treatment of pregnancy complicated by Krukenburg tumor. According to domestic and international studies, diagnosis should be confirmed based on clinical manifestations and imaging examinations, treatment should be individualized according to the patient′s condition, gestational age, maternal-fetal status. Therefore, more research is needed on this rare disease to provide recommendations for early detection, diagnosis and treatment methods. This review summarizes the progress in the diagnosis and treatment of Krukenberg tumor during pregnancy, providing a valuable reference for clinical practice.

Key words: Pregnancy, Krukenberg tumor, Ovarian neoplasms, Diagnosis, Therapy