Abstract: Glucose metabolic disorder can cause Impaired fasting glucose（IFG） and Impaired glucose tolerance（IGT），even Diabetes Mellitus，Obesity and Hypertension.These diseases are caused by glucose，lipid and protein metabolic disorder，which are closely related with many kinds of carcinoma，such as rectal cancer，breast cancer and of couse endometrial cancer. Refering to the essential aspect ，insulin resistance maybe the most important reason.In the future，we can increase the curative ratio of endometrial cancer through improving the glucose metabolic disturbance，controling body weight and treating Diabetes，all of which may turn into efficient measures of the prevention and treatment of Endometrial carcinoma.

Key words: Glucose metabolism disorders, Endometrial neoplasms, Carcinoma, Insulin resistance