Abstract: Endometrial hyperplasia is one of the most common gynecological diseases，which affects a large number of women′s health. Most patients are more and more tend to be younger women. At present，there are several methods to evaluate endometrium, such as transvaginal sonography（TVS），saline infusion sonohysterography（SIS），hysteroscopy（HYS） +stereotactic biopsy，dilatation and curettage，Pipelle endometrial sampling device. TVS plays a key role in screening and diagnosing of endometrial hyperplasia，which is a diagnostic tool for evaluating endometrium in women of reproductive age. SIS is used to assess local lesions of endometrial cavity，which is a safe，cost-effective，easy to use tool. HYS and stereotactic biopsy is the "gold standard" for assessment of endometrium. There is no evidence that any use of intrauterine fluid diagnostic process may make endometrial cancer cells into the peritoneum，which results in deterioration of the disease or reduce prognosis of endometrial hyperplasia. Pipelle endometrial sampling without anesthesia is vacuum sampling，which is the most minimally invasive in the current practice. The diagnostic accuracy rate of Pipelle endometrial sampling is almost the same to dilatation and curettage.

Key words: Endometrial hyperplasia, Diagnosis, Ultrasonography, Hysteroscopy