Abstract:

Endometriosis is a common gynecological disease, but the probability of malignant transformation is low, and the probability of malignant transformation of ovarian and fallopian tube endometriosis to clear cell carcinoma is lower, and there are few reports on this. Our hospital has found a case of ovarian and fallopian tube compound endometriosis malignant transformation into clear cell carcinoma. The patient was hospitalized due to abdominal distension. Imaging examination revealed huge pelvic masses and ascites, and multiple nodules in the omentum, which were considered to be metastatic. So, ovarian malignant tumor cytoreductive surgery was performed. The postoperative pathological biopsy was consistent with clear cell carcinoma, and the cancer foci were distributed in both fallopian tubes and the right ovary. Intravenous chemotherapy was performed postoperatively, in the first cycle, paclitaxel liposome and carboplatin were used, in the second cycle, bevacizumab was added to the original chemotherapy regimen for targeted therapy. Now the 6th cycle of chemotherapy, post chemotherapy evaluation has been done, there was no obvious adverse reaction, and no tumor recurrence or metastasis was found.

Key words: Endometriosis, Ovary, Fallopian tubes, Adenocarcinoma, clear cell, Diagnosis, Therapy, Prognosis