Abstract: Most of polycystic ovarian syndrome （PCOS） women had impedimental glucose metabolism，lipid metabolism， and metabolic syndrome， which result in increased risks of diabetes mellitus and cardiovascular diseases. Oral contraceptive pills（COC）， as the first line therapy for antiandrogen and menstrual regulation in PCOS women， obtained satisfactorily clinical outcome. However， it may aggravate metabolic problems when used in PCOS women with metabolic dysfunction. A new kind of COC—Yasmin consisted of drospirenone which acted as antiandrogen and anti-aldosterone has almost no negative effect on glucose metabolism， should be one of choices for PCOS women with metabolic dysfunction.

Key words: Polycystic ovary syndrome, Insulin resistance, Contraceptives, oral, Glucose metabolism disorders