Abstract: Objective：To observe the curative effects of "ataraxia electroacupuncture" on perimenopausal syndrome（PMS）. Methods：60 cases of PMS were randomly divided into a treatment group and a control group，30 cases in each group．The treatment group were treated with "ataraxia electroacupuncture" and the control group with oral administration of Climen tablets for 3 courses of the treatment. The therapeutic effects and changes of scores of Kupperman index（KI） were investigated before and after treatment for 1 month，3 month，finished treatment for 3 month，and 6 month，and serum estradiol（E2），follicle stimulating hormone（FSH），luteinizing hormone（LH） levels before and after treatment were observed. Results：The total effective rate was 90.00％ in treatment group while 93.33% in control group，with no significant difference between the two groups（P＞0.05）. After treatment，the scores of KI in every time point was significantly decreased（P＜0.01），but there was no significant difference between the two groups in the same time point（P＞0.05）. And the scores of KI were increased slightly in 3 month and 6 month after treatment，which was more clear in the control group，but there was no significant difference between the two groups（P＞0.05）. And after treatment，serum E2，FSH and LH levels were all better than before treatment in both group（P＜0.01），but there were no significant differences between the two groups（P＞0.05）. Conclusions："Ataraxia electroacupuncture" is safe and effective for treatment of perimenopausal syndrome，and worth promoting.

Key words: Climacteric syndrome, Electroacupuncture, Acupuncture-moxibustion, Randomized controlled trial