自发性卵巢过度刺激综合征合并卵巢破裂一例并文献复习

doi:10.12280/gjfckx.20201199

摘要/Abstract

摘要：

卵巢过度刺激综合征（ovarian hyperstimulation syndrome,OHSS）是一种医源性疾病,常发生于辅助生殖技术中的控制性超排卵患者,但也可见于自发排卵周期,尤其是多胎妊娠、甲状腺功能减退和多囊卵巢综合征患者,自然妊娠并发OHSS的发生率极低,严重影响患者身体健康,甚至可危及生命。报道1例自发性卵巢过度刺激综合征（spontaneous ovarian hyperstimulation syndrome,sOHSS）并发卵巢破裂的病例,并探讨sOHSS的发病机制、临床表现、并发症、鉴别诊断及治疗,为临床诊治提供参考依据。

关键词: 自发性卵巢过度刺激综合征, 卵巢过度刺激综合征, 排卵诱导, 发病机制, 基因突变, 危险因素, 诊断, 治疗

Abstract:

Ovarian hyperstimulation syndrome (OHSS) is an iatric disease frequently occurred in patients with controlled ovarian hyperstimulation, but also can be observed in spontaneous ovulation cycles, especially those with multiple-pregnancy, hypothyroidism, polycystic ovary syndrome. The incidence of natural pregnancy complicated with OHSS is very low, which seriously affects the health of patients and even endangers their lives. This paper reported a case of spontaneous ovarian hyperstimulation syndrome (sOHSS) with ovarian rupture, and discussed the pathogenesis, clinical manifestations, complications, differential diagnosis and treatment of sOHSS, so as to provide a reference for clinical treatment.

Key words: Spontaneous ovarian hyperstimulation syndrome, Ovarian hyperstimulation syndrome, Ovulation induction, Pathogenesis, Gene mutations, Risk factors, Diagnosis, Therapy

王欣欣, 钱永红. 自发性卵巢过度刺激综合征合并卵巢破裂一例并文献复习[J]. 国际妇产科学杂志, 2021, 48(5): 528-531.

WANG Xin-xin, QIAN Yong-hong. A Case of Spontaneous Ovarian Hyperstimulation Syndrome with Ovarian Rupture and Literature Review[J]. Journal of International Obstetrics and Gynecology, 2021, 48(5): 528-531.

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