国际妇产科学杂志 ›› 2021, Vol. 48 ›› Issue (6): 684-690.doi: 10.12280/gjfckx.20211040

• 产科生理及产科疾病:标准与指南 • 上一篇    下一篇

2021美国妇产科医师学会实践公告“自发性早产的预测和预防指南”解读

蒋湘, 应豪()   

  1. 201204 上海市第一妇婴保健院产科,同济大学医学院,上海市母胎医学重点实验室
  • 收稿日期:2021-11-10 出版日期:2021-12-15 发布日期:2021-12-30
  • 通讯作者: 应豪 E-mail:stephenying2011@126.com
  • 基金资助:
    国家自然科学基金面上项目(82071678);促进市级医院临床技能与临床创新三年行动计划重大临床研究项目(SHDC2020CR2059B);上海市2021年度“科技创新行动计划”实验动物研究领域项目(21140903800);浦东卫生行业科研专项(PW2020E-1)

The Interpretation of 2021 ACOG Practice Bulletin: Prediction and Prevention of Spontaneous Preterm Birth

JIANG Xiang, YING Hao()   

  1. Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai Key Laboratory of Maternal and Fetal Medicine, Shanghai 201204, China
  • Received:2021-11-10 Published:2021-12-15 Online:2021-12-30
  • Contact: YING Hao E-mail:stephenying2011@126.com

摘要:

早产是导致新生儿死亡及近远期并发症的主要原因,其中70%~80%为自发性早产(spontaneous preterm birth,SPB),20%~30%为医源性早产。近年国内外早产率呈上升趋势,研究人员通过开展早产相关研究以致力于改善早产相关预后。2021年8月美国妇产科医师学会(American College of Obstetricians and Gynecologists,ACOG)发布了实践公告第234号文件“自发性早产的预测和预防”,该指南结合最新研究进展为临床实践提供指导,内容涵盖近年来早产率的变化趋势及其影响因素,如何通过干预可干预的危险因素降低早产风险,对于不同人群如何进行个体化的SPB风险预测,不同人群中不同预防方法的预防疗效评价等。针对该指南中的要点进行了解读,旨在为早产相关的临床实践提供循证依据。

关键词: 早产, 预测, 指南, 自发性早产, 预防, 美国妇产科医师学会

Abstract:

Preterm birth is the main cause of neonatal death and short-term and long-term complications, of which 70%~80% are spontaneous preterm birth (SPB), and the other 20%~30% are iatrogenic preterm birth. The rate of preterm birth has been increasing in recent years and efforts were made to improve the prognosis of preterm birth. In August 2021, the American College of Obstetricians and Gynecologists (ACOG) issued the practice bulletin No. 234 "Prediction and Prevention of Spontaneous Preterm Birth", covering the increased preterm birth rate and its associated risk factors, measures to reduce the risk of preterm birth by intervening modifiable risk factors, strategies to assess the risk of preterm birth individually and prevent preterm birth. This paper interpreted the main points of its recommendation in order to provide evidence-based basis for clinical practice related to preterm delivery.

Key words: Premature birth, Forecasting, Guidebooks, Spontaneous preterm birth, Prevention, ACOG