国际妇产科学杂志 ›› 2022, Vol. 49 ›› Issue (6): 644-648.doi: 10.12280/gjfckx.20220318

• 妇科肿瘤研究:病例报告 • 上一篇    下一篇

绝经后子宫内膜腺肉瘤致子宫内翻一例并文献复习

叶圣龙, 张璐芳()   

  1. 100191 北京,国家妇产疾病临床研究中心,北京大学第三医院妇产科
  • 收稿日期:2022-04-26 出版日期:2022-12-15 发布日期:2023-01-11
  • 通讯作者: 张璐芳 E-mail:lufang_z@sina.com

Uterine Inversion Caused by Endometrial Adenosarcoma in Postmenopausal: A Case Report and Literature Review

YE Sheng-long, ZHANG Lu-fang()   

  1. National Clinical Research Center for Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China
  • Received:2022-04-26 Published:2022-12-15 Online:2023-01-11
  • Contact: ZHANG Lu-fang E-mail:lufang_z@sina.com

摘要:

绝经后慢性子宫内翻是一种罕见病,报告1例老年女性因子宫内膜腺肉瘤导致子宫内翻,继发感染、尿潴留及静脉血栓栓塞的病例。患者因绝经后阴道出血就诊,期间发现肿物自阴道逐步脱出,经专科查体及影像学检查,考虑是继发于宫底肿物的慢性完全性子宫内翻。病程中患者先后出现感染、尿潴留及左下肢全程静脉血栓栓塞。经多学科会诊,最终于椎管内麻醉下行经腹会阴联合子宫及双附件切除术,术后病理示子宫内膜腺肉瘤,临床拟诊ⅠA期,患者拒绝再分期手术及辅助治疗,术后随访2年无新发肿物。针对该类罕见疾病,结合超声及盆腔磁共振成像典型征象可尽早明确诊断,其治疗需针对原发肿瘤、继发于内翻子宫的并发症及患者自身合并症,制定个体化的围手术期管理方案。

关键词: 子宫内翻, 绝经后期, 感染, 静脉血栓形成, 子宫内膜肿瘤, 腺肉瘤, 病例报告

Abstract:

Postmenopausal chronic uterine inversion is a rare disease. A case of uterine inversion caused by endometrial adenosarcoma in an elderly woman, complicating with infection, urinary retention and venous thromboembolism was reported. The patient was hospitalized due to postmenopausal vaginal bleeding. During that period, it was found that the tumor gradually prolapse from the vagina. After gynecologic physical examination and imaging examination, it was considered that the chronic complete uterine inversion secondary to the tumor in the fundus of the uterus. During the course of the disease, the patient developed infection, urinary retention and left lower extremity venous thromboembolism. After multi-disciplinary consultation, transabdominal perineum combined with hysterectomy and bilateral adnexa resection were finally performed under spinal canal anesthesia in our hospital. The postoperative pathology showed endometrial adenosarcoma and the clinical diagnosis was stage ⅠA. The patient refused to undergo re-staged surgery and adjuvant treatment. There was no new tumor found in 2 years follow-up. For this kind of rare disease, combined with the typical signs of ultrasound and pelvic MRI, the diagnosis can be made as soon as possible. The treatment should be aimed at the primary tumor, complications secondary to the inverted uterus and the patient′s own complications, to develop an individualized perioperative management scheme.

Key words: Intrauterine inversion, Postmenopause, Infection, Venous thrombosis, Endometrial neoplasms, Adenosarcoma, Case reports