国际妇产科学杂志 ›› 2025, Vol. 52 ›› Issue (5): 508-511.doi: 10.12280/gjfckx.20250206

• 妇科肿瘤研究: 病例报告 • 上一篇    下一篇

盆腔腹膜恶性间皮瘤一例

朱冉冉, 于春丽()   

  1. 271000 山东省泰安市中心医院妇科
  • 收稿日期:2025-03-04 出版日期:2025-10-15 发布日期:2025-10-16
  • 通讯作者: 于春丽 E-mail:Chunliyu1970@163.com

A Case of Malignant Mesothelioma of the Pelvic Peritoneum

ZHU Ran-ran, YU Chun-li()   

  1. Department of Gynecology, Tai'an Central Hospital, Tai'an 271000, Shandong Province, China
  • Received:2025-03-04 Published:2025-10-15 Online:2025-10-16
  • Contact: YU Chun-li E-mail:Chunliyu1970@163.com

摘要:

报告1例腹膜恶性间皮瘤(peritoneal malignant mesothelioma,PMM)病例,患者因扪及腹部肿物就诊,彩色超声提示盆腔内低回声团包块,术前拟诊为盆腔恶性肿瘤,遂行腹腔镜探查术,术中切除双侧输卵管及卵巢表面病灶,术中病理未能明确肿物性质,术后常规病理经过进一步会诊确诊为恶性肿瘤,考虑恶性间皮瘤,不除外来自腹膜。遂行肿瘤细胞减灭术,术后患者症状缓解,拒绝进一步治疗。PMM是一种临床罕见、源于浆膜间皮和间皮下层细胞的高侵袭性恶性肿瘤,好发于胸膜和腹膜,与石棉暴露密切相关。该病起病隐匿,缺乏典型症状,且影像学特异性不高,在临床诊治中具有一定难度。临床确诊时多为晚期,预后较差。PMM治疗方法主要是肿瘤细胞减灭术联合腹腔内热灌注化疗。

关键词: 盆腔肿瘤, 腹膜肿瘤, 恶性间皮瘤, 诊断, 治疗

Abstract:

A case of peritoneal malignant mesothelioma (PMM) is reported. The patient presented due to a palpable abdominal mass. Color Doppler ultrasound indicated a hypoechoic mass in the pelvic cavity. Before the operation, the patient was tentatively diagnosed with a pelvic malignant tumor. Subsequently, a laparoscopic exploration was performed, and the lesions on the surface of the bilateral fallopian tubes and ovaries were resected during the operation. The nature of the mass could not be determined by introperative pathological examination. After the operation, the routine pathological examination, following further consultation, confirmed it as a malignant tumor, suspected to be a malignant mesothelioma, possibly originating from the peritoneum. Then, a cytoreductive surgery was carried out. After the operation, the patient's symptoms were relieved, but the patient refused further treatment. PMM is a clinically rare, highly invasive malignant tumor originating from serosal mesothelial and sub-mesothelial cells. It commonly occurs in the pleura and peritoneum and is closely associated with asbestos exposure. The disease has an insidious onset, lacks typical symptoms, and has low imaging specificity, posing certain difficulties in clinical diagnosis and treatment. Most cases are diagnosed at an advanced stage, with a poor prognosis. The main treatment for PMM is cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy.

Key words: Pelvic neoplasms, Peritoneal neoplasms, Mesothelioma, malignant, Diagnosis, Therapy