国际妇产科学杂志 ›› 2010, Vol. 37 ›› Issue (1): 43-46.

• 综述 • 上一篇    下一篇

脂肪细胞因子chemerin的研究进展

王晓娟;颜建英   

  1. 350004福州,福建医科大学研究生学院(王晓娟);福建省妇幼保健院妇产科(颜建英)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-02-15 发布日期:2010-02-15
  • 通讯作者: 颜建英

Research Progress on Adipokine chemerin

WANG Xiao-juan;YAN Jian-ying   

  1. Postgraduate Institute of Fujian Medical University Fuzhou 350004, China(WANG Xiao-juan); Department of Obstetrics and Gynecology, Fujian Women and Children Health Hospital, Fuzhou 350001, China(YAN Jian-ying)
  • Received:1900-01-01 Revised:1900-01-01 Published:2010-02-15 Online:2010-02-15
  • Contact: YAN Jian-ying

摘要: chemerin是新近发现的一种脂肪细胞因子,在免疫应答、炎症反应、脂肪细胞分化成熟、脂质代谢等方面发挥作用。研究发现:chemerin是代谢综合征的一个新的标志物,与动脉粥样硬化、胰岛素抵抗存在相关性,糖尿病小鼠脂肪组织中chemerin表达明显下降,明确其作用机制和功能,可能为妊娠期相关疾病,如代谢综合征、妊娠期糖尿病提供新的预防、治疗策略。
【关键词】 chemerin; 妊娠期糖尿病; 代谢综合征; 脂肪细胞因子

关键词: chemerin, 妊娠期糖尿病, 代谢综合征, 脂肪细胞因子

Abstract: Chemerin is a novel adipokine with effects on immunity, inflammation, adipocyte differentiation
and lipid metabolism. Recent studies have indicated that chemerin is a new independent marker of metabolic syndrome.Understanding the mechanisms and function of chemerin may provide novel effective therapeutic strategies to treat and prevent relative diseases.

Key words: chemerin, Gestational diabetes mellitus, Metabolic syndrome, Adipokine