国际妇产科学杂志

国际妇产科学杂志 ›› 2010, Vol. 37 ›› Issue (4): 271-273.

• 综述 • 上一篇    下一篇

卵巢癌抗血管靶向治疗临床研究进展

胡元晶，薛凤霞   

  1. 300052 天津市中心妇产科医院（胡元晶），天津医科大学总医院（薛凤霞）

  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-08-15 发布日期:2010-08-15

The Progress in Anti-Vascular Target Therapy in Ovarian Cancer

HU Yuan-jing，XUE Feng-xia   

  1. Tianjin Central Hospital of Obstetrics & Gynecology，Tianjin 300052，China（HU Yuan-jing）；Tianjin Medical University General Hospital，Tianjin 300052，China（XUE Feng-xia）
  • Received:1900-01-01 Revised:1900-01-01 Published:2010-08-15 Online:2010-08-15

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摘要： 靶向治疗是针对肿瘤组织有别于正常组织的特征，给予有针对性的治疗，从而达到较好治疗效果和较小的不良反应。目前抗肿瘤靶向治疗研究中最多的是抗血管治疗，不断研发出许多新的药物，并已广泛用于临床试验。对近年来卵巢癌抗血管靶向治疗的临床研究加以综述，以介绍这一新治疗方法在卵巢癌中的治疗现状、面临问题和前景。

关键词: 卵巢肿瘤, 血管内皮生长因子类, 治疗, 临床试验

Abstract: Target therapy focus on the tumor's characteristics which are different from normal tissues. So as to gain higher therapeutic effect with lower adverse effect. At present，most of the research of target therapy is about anti-vascular therapy.Intense researches and development activities have resulted in a variety of investigational agents，a number of which are currently be used in clinical experiments. This paper reviewed the clinical trials of anti-vascular target therapy in ovarian cancer，in order to know about the current situation and the prospective research of the treatment in ovarian cancer.

Key words: Ovarian neoplasms, Vascular endothelial growth factors, Therapy, Clinical trial