国际妇产科学杂志 ›› 2011, Vol. 38 ›› Issue (4): 261-262.

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以转化医学的观念促进子宫内膜异位症的研究

郎景和

  

  1. 100730 北京袁 中国医学科学院 中国协和医学院 北京协和医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-08-15 发布日期:2011-08-15
  • 通讯作者: 郎景和

Translational Medicine in Improving Endometriosis Researches

LANG Jing-he   

  1. Department of Obstetrics and Gynecology,Peking Union Medical College Hospital,Chinese Academy of Medicine Sciences,Beijing 100730,China
  • Received:1900-01-01 Revised:1900-01-01 Published:2011-08-15 Online:2011-08-15
  • Contact: LANG Jing-he

摘要:
子宫内膜异位症是育龄妇女的常见病,其发病机制不清、治疗结果不满意。在位内膜、干细胞及古子宫的重要作用引起研究者的重视。以此诠释子宫内膜异位症的发生,并对其做出精准的诊断、拓展治疗模式以及探索预防措施均有理论和实际意义。“源头诊断”、“源头治疗”是子宫内膜异位症诊治的新观念,生物学检测为流行病调查提供了可能,表明转化医学在其中的促进作用。

关键词: 子宫内膜异位症, 在位内膜, 干细胞, 古子宫, 转化医学, 生物技术, 生物转化

Abstract: Endometriosis(EMs) typically affects women of reproductive age. The underlining mechanisms of EM are not fully disclosed and treatment regimens do not provide satisfactory effects. Eutopic endometrium, stem cells and archimetra have been highly recognized in explaining the development of endometriosis, which also have great contributions to disease diagnosis, therapy development and preventive measures both theoretically and practically. New concepts such as“source of diagnosing”and“source of healing”are introduced into diagnosis and management of EM, epidemiology researches are possible with the help of bioassays, these all suggest an important role of translational medicine in optimizing EM researches.

Key words: Endometriosis, Eutopic Endometrium, Stem cell, Archimetra, Translational medicine, Biotechnology