国际妇产科学杂志

国际妇产科学杂志 ›› 2011, Vol. 38 ›› Issue (4): 263-266.

• 综述 • 上一篇    下一篇

子宫内膜异位症和细胞迁移


郭晓燕, 吴瑞瑾 , 林 俊   

  1. 310006 杭州,浙江大学医学院附属妇产科医院
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-08-15 发布日期:2011-08-15
  • 通讯作者: 林 俊

Endometriosis and Cell Migration

GUO Xiao-yan, WU Rui-jin, LIN Jun   

  1. Woman′s Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2011-08-15 Online:2011-08-15
  • Contact: LIN Jun

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摘要： 子宫内膜异位症（EMs）是常见妇科疾病，其病因仍未清楚。预防EMs的发生是当前备受关注的课题之一。子宫内膜组织细胞迁移是EMs患者异位病灶形成的前提条件，调节子宫内膜细胞的迁移很可能会影响子宫内膜组织异位病灶的形成。深入了解细胞迁移和EMs形成间的相关机制非常重要。综述国内外关于子宫内膜组织细胞迁移的研究方法以及正常人群和EMs患者子宫内膜组织细胞的迁移能力的差异及其可能机制等相关研究，以期为EMs的预防提供思路。

关键词: 子宫内膜异位症, 细胞运动, 细胞迁移分析, 干细胞

Abstract: Endometriosis（EMs）, a commmom gynecological disease, has still an undetermined etiology. How to prevent EMs is one of the hot topics of intensive interest. Endometrial cell migration is the fundamental stage of the EMs pathological process. Regulation of cell migration may affect the ability of endometrial tissue to implant, grow and survive. Therefore, it is important to understand the mechanism of endometrial cell migration in physiological and pathological processes. In this review，difference in cell migration between woman with and without endometriosis and its possible molecular mechanism will be discussed, which may provide new thoughts for EMs prevention.

Key words: Endometriosis, Cell movement, Cell migration assays, Stem cells