国际妇产科学杂志

国际妇产科学杂志 ›› 2011, Vol. 38 ›› Issue (6): 479-482.

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阴道微生态研究进展


肖冰冰,廖秦平   

  1. 100034 北京大学第一医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-12-15 发布日期:2011-12-15

Research Progress in Vaginal Ecosystem

XIAO Bing-bing，LIAO Qin-ping   

  1. Department of Obstetrics and Gynecology，Peking University First Hospital，Beijing 100034，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2011-12-15 Online:2011-12-15

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摘要： 女性阴道是一个独特、动态变化的微生态体系，其中存在多种正常的微生物群落，其与宿主、环境之间构成了相互制约、相互协调的微生态平衡，对维持健康的阴道微生态发挥着重要的作用。随着非培养方法在阴道微生态研究中的应用，研究者对阴道菌群有了更加全新的认知，对“正常菌群”的概念进行不断的修订。乳酸菌是阴道优势菌群，其随着内源性和外源性因素的改变而不断发生变化，且不同地域、不同种族女性阴道内的优势菌群存在差异。

关键词: 阴道, 乳杆菌属, 年龄因素, 抗菌药, 避孕

Abstract: The vagina is a dynamic and finely tuned ecosystem in which homeostasis depends on mutually beneficial interactions between a human female and her resident microorganisms. In recent years，the development and introduction of cultivation-independent molecular-based techniques have provided new information about the composition of normal vaginal flora，“normal flora” is a concept currently being redefined.Dominance by lactic-acid producing microbes appears to be the cornerstone of microbial health. Numerous factors（both internal and external） have the potential to disrupt the vaginal ecosystem's fragile balance，and different racial groups，different geographical region have significant difference in what is the dominant vaginal organisms.

Key words: Vagina, Lactobacillus, Age factors, Anti-bacterial agents, Contraception