国际妇产科学杂志 ›› 2012, Vol. 39 ›› Issue (6): 606-608.

• 论著 • 上一篇    下一篇

降钙素原对妊娠妇女宫内感染诊断的临床意义

陈炎添, 熊 燕, 苏雪棠 , 石 胜, 黄伟刚, 范修敬 , 李 莹   

  1. 529000 广东省江门市,江门市人民医院检验科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2012-12-15 发布日期:2012-12-15

The Clinical Significance of Procalcitonin for Diagnosis of the Pregnant Women with Intrauterine Infection

CHEN Yan-tian,XIONG Yan,SU Xue-tang,SHI Sheng,HUANG Wei-gang,FAN Xiu-jing,LI Ying   

  1. Department of Clinical Laboratory,Jiangmen People′s Hospital,Jiangmen 529000,Guangdong Province,China
  • Received:1900-01-01 Revised:1900-01-01 Published:2012-12-15 Online:2012-12-15

摘要: 目的:评价血清降钙素原(procalcitonin,PCT)对妊娠妇女宫内感染诊断的临床价值。方法:随机抽取到宫内感染的妊娠妇女及正常妊娠检查的妇女,主要观察细菌感染者及病毒感染者血清PCT的情况,并比较同期白细胞介素6(IL-6)、C-反应蛋白(CRP)、白细胞(WBC)计数、中性粒细胞百分率(N)的水平。结果:PCT对细菌感染的特异度(87.9%)、敏感度(92.4%)、准确度(83.5%)、阳性预测值(80.4%)、阴性预测值(91.7%)和阳性率(88.2%)均较高于其他项目,细菌感染组与病毒感染组比较差异有统计学意义(P<0.05)。结论:血清PCT可作为妊娠妇女宫内感染的辅助诊断,也可作为鉴别细菌感染和病毒感染的依据,同时可有效地指导临床抗生素的应用及评估疗效。

关键词: 降钙素原, 宫内感染, 白细胞介素6, C反应蛋白质

Abstract: Objective:To evaluate the clinical value of procalcitonin for diagnosis of the pregnant woman with intrauterine infection. Methods:We chose intrauterine infection of the pregnant woman and the nomal pregnant woman randomly,the main observation of the patients with bacterial and viral infection of PCT,and to compare the same period Ⅱ-6,CRP,WBC,N levels. Results:Speciticity(87.9%),sensitivity(92.4%), accuracy(83.5%),the positive predictive value(80.4%), the negative predictive value(91.7%) and the positive rate (88.2%) of PCT for the patients with bacterial infection were higher than other projects.The patients with bacterial infection group were higher than the patients with viral infection group(P<0.01). Conclusions:
PCT can be used as the auxiliary diagnosis of the pregnant woman with intrauterine infection,and can effectively guide the clinical use of antibiotics to assess the therapeutic effect.

Key words: Procalcitonin, Intrauterine infection, Interleukin-6, C-reactive protein