国际妇产科学杂志 ›› 2013, Vol. 40 ›› Issue (2): 156-159.

• 综述 • 上一篇    下一篇

卵巢颗粒细胞瘤的诊疗进展


奚滕滕, 冯兰兰, 刘雪影, 张建平
  

  1. 215006江苏苏州,苏州大学附属第一医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2013-04-15 发布日期:2013-04-15
  • 通讯作者: 张建平

The Progress of Diagnosis and Treatment for Granulosa Cell Tumors

XI Teng-teng,FENG Lan-lan,LIU Xue-ying,ZHANG Jian-ping   

  1. The First Affiliated Hospital of Soochow University,Suzhou 215006,Jiangsu Province,China
  • Received:1900-01-01 Revised:1900-01-01 Published:2013-04-15 Online:2013-04-15
  • Contact: ZHANG Jian-ping

摘要: 卵巢颗粒细胞瘤是相对少见的卵巢性索间质细胞肿瘤,因发病初期多有内分泌相关症状,而使得该肿瘤容易被早期发现。各种分子生物学指标在该病的诊断及随访中发挥着重要的作用。手术是其重要的治疗措施,化疗、放疗、激素治疗及分子生物靶向治疗也是重要的治疗方法。对这类患者采取合理的治疗手段,相对于其他的卵巢恶性肿瘤,可以达到较高的存活率。

关键词: 颗粒细胞瘤, 卵巢肿瘤, 分子生物学, 莱迪希细胞瘤, 治疗

Abstract: Granulosa cell tumours (GCTs) are relatively rare sex cord stromal tumours of the ovary. Most of them are hormone-producing,and can be initially diagnosed in early stage. Molecular biology markers are useful in diagnosis and follow-up. Surgery is an important treatment,while chemotherapy,radiotherapy,hormone therapy and molecular-targeted therapy also play important roles. With appropriate treatment,a better survival rate can be achieved against other ovarian malignancies.

Key words: Granulosa cell tumour, Ovarian neoplasms, Molecular biology, Leydig cell tumor, Therapy