国际妇产科学杂志

国际妇产科学杂志 ›› 2015, Vol. 42 ›› Issue (1): 17-20.

• 综述 • 上一篇    下一篇

儿童及青少年卵巢恶性肿瘤

周锦英，卞丽红   

  1. 100071 北京，中国人民解放军第三○七医院妇科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2015-02-15 发布日期:2015-02-15
  • 通讯作者: 卞丽红

Childhood Ovarian Malignancy

ZHOU Jin-ying，BIAN Li-hong   

  1. Department of Gynecology，The 307th Hospital of Chinese People′s Liberation Army，Beijing 100071，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-02-15 Online:2015-02-15
  • Contact: BIAN Li-hong

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摘要： 卵巢恶性肿瘤在＜19岁的青少年、儿童中非常罕见，不到儿童所有恶性肿瘤的1%，却是最常见的青少年妇科恶性肿瘤。与成人卵巢肿瘤主要来源于上皮组织不同，青少年儿童卵巢肿瘤以生殖细胞肿瘤为主，包括畸胎瘤、性腺母细胞瘤、内胚窦瘤（又称卵黄囊瘤）、胚胎癌、多胚癌及绒癌。非生殖细胞肿瘤包括性索-间质肿瘤和上皮性肿瘤，性索-间质肿瘤包括卵泡膜-纤维瘤、Sertoli-Leydig细胞肿瘤及幼年型颗粒细胞肿瘤。与成人卵巢癌就诊时大多为晚期不同，青少年、儿童卵巢肿瘤患者就诊时大多处于临床早期，可行保守性手术。有效地治疗肿瘤的同时保留卵巢及生育功能是青少年卵巢肿瘤治疗的目标。

关键词: 儿童, 青少年, 卵巢肿瘤, 妇科外科手术, 抗肿瘤联合化疗方案

Abstract: Pediatric ovarian malignant tumors are an uncommon type of childhood cancer and account for only 1% of all malignancies in children. The main histopathologic type is germ cell tumor, which is different from adult ovarian tumor deriving mainly from epithelial tissue, including teratoma, gonadoblastoma, endodermal sinus tumor (also known as yolk sac tumor), polyembryony cancer, and embryonal carcinoma, choriocarcinoma. Non germ cell tumors include sex cord stromal tumor and epithelial tumors, sex cord stromal tumor including theca fibrous tumor, Sertoli-Leydig cell tumor and juvenile granulosa cell tumor. Most of adolescent patients are in early clinical stage at their first medical treatment and conservative operation is feasible. Effective treatment of tumors with fertility sparing are the aims of treatment for adolescent ovary tumors.

Key words: 【Keywords】 procedures, Antineoplastic combined chemotherapy protocols