国际妇产科学杂志 ›› 2025, Vol. 52 ›› Issue (2): 132-136.doi: 10.12280/gjfckx.20241092

• 产科生理及产科疾病:综述 • 上一篇    下一篇

产前抑郁致子代精神疾病的研究进展

苏一雯, 石中华()   

  1. 213000 南京医科大学常州医学中心,常州市妇幼保健院
  • 收稿日期:2024-11-27 出版日期:2025-04-15 发布日期:2025-04-22
  • 通讯作者: 石中华 E-mail:jesse_1982@163.com
  • 基金资助:
    常州市妇幼医学重点实验室(CM20240013)

Research Progress on Antenatal Depression Causing Mental Disorders in Offspring

SU Yi-wen, SHI Zhong-hua()   

  1. Changzhou Medical Center, Nanjing Medical University, Changzhou Maternity and Child Health Care Hospital, Changzhou 213000, Jiangsu Province, China
  • Received:2024-11-27 Published:2025-04-15 Online:2025-04-22
  • Contact: SHI Zhong-hua E-mail:jesse_1982@163.com

摘要:

产前抑郁是目前发病率较高的一种妊娠期心理疾病,不仅会增加其他妊娠期并发症和不良妊娠结局的发生率,而且会增加子代患精神疾病的风险。近年来有研究涉及产前抑郁导致子代精神疾病的研究,发现产前抑郁与儿童抑郁障碍、儿童注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)和孤独症谱系障碍(autism spectrum disorder,ASD)显著相关,但其潜在机制尚不清楚。回顾产前抑郁的评估、预测以及其所导致的常见子代精神疾病,以指导临床实践和科学研究。

关键词: 孕妇, 抑郁症, 儿童, 注意力缺陷障碍伴多动, 孤独症谱系障碍, 儿童抑郁障碍

Abstract:

Antenatal Depression is a prevalent psychological disorder during pregnancy, which not only increases the risk of other pregnancy complications and adverse outcomes but also increases the likelihood of mental disorders in offspring. In recent years, there have been studies on antenatal depression leading to mental disorders in offspring, and it has been found that antenatal depression is significantly associated with childhood depression, attention deficit hyperactivity disorder (ADHD), and autism spectrum disorder (ASD). However, the underlying mechanisms remain unclear. This paper provides a comprehensive review of the assessment and prediction of antenatal depression, and the common mental disorders in offspring resulting from antenatal depression, aiming to guide clinical practice and scientific research.

Key words: Pregnant women, Depressive disorder, Child, Attention deficit disorder with hyperactivity, Autism spectrum disorder, Childhood depression disorder