关键词: 儿童, 无性细胞瘤, 卵巢肿瘤, 诊断, 治疗, 病例报告

Abstract:

Children ovarian dysgerminoma is uncommon in clinic practice. Combined with the history and the auxiliary examination, surgery in children ovarian dysgerminoma is the preferred approach. With the development and progress of the comprehensive treatment model, we need to consider the protection of children′s fertility and the management of ovarian malignant tumor after surgical treatment. Here we report the data of a 12-year-old child with ovarian dysgerminoma. The patient first seen in the department of pediatrics due to abdominal pain, and then went to the department of gynecology after finding pelvic mass. Anal examination indicated that a mass of about 7.0 cm×6.0 cm, quality medium, border clear and movable could be palpated on the right side of the pelvic cavity. The examination of relevant tumor markers showed that alpha-fetoprotein and carbohydrate antigen 125 increased slightly. Laparotomy and intraoperative freezing suggested that benign lesions were considered in the left ovary and malignant lesions in the right ovary, so right adnexectomy+excision of left ovarian cyst was performed. Adjuvant chemotherapy and goserelin castration were given to protect ovarian function after surgery. The patient has been followed up for 11 months and has regular menstruation without special discomfort. The diagnosis and treatment process and characteristics of ovarian dysgerminoma in children were reviewed in order to improve clinicians′ consideration of the diagnosis, treatment and management of this disease.

Key words: Child, Dysgerminoma, Ovarian neoplasms, Diagnosis, Therapy, Case reports