卵巢原发性弥漫大B细胞淋巴瘤一例并文献复习

doi:10.12280/gjfckx.20220235

摘要/Abstract

摘要：

卵巢弥漫大B细胞淋巴瘤（diffuse large B cell lymphoma，DLBCL）是一种临床少见的发生于卵巢的恶性肿瘤，其发病机制尚不清晰，临床表现及辅助检查无明显特异性，术前诊断困难，确诊只能依靠组织病理结果及免疫组织化学结果，极易与卵巢其他恶性肿瘤相混淆，错过最佳治疗时机会延误病情。报道我院收治的1例卵巢DLBCL病例，患者以腹胀为主诉就诊，无其他不适，影像学检查不典型，入院初步诊断为盆腔肿物，通过行剖腹探查术得以明确诊断，给予手术及化学药物治疗。回顾性分析该患者的临床资料，复习相关文献，旨在加深临床医生对该病的认识，切实提高临床诊治能力。

关键词: 卵巢肿瘤, 淋巴瘤, 大B细胞, 弥漫性, 淋巴瘤, 诊断, 治疗, 病例报告

Abstract:

Diffuse large B cell lymphoma (DLBCL) is a rare malignant tumor of the ovary, the pathogenesis of which is still unclear, and the clinical manifestations and auxiliary examination are not specific, preoperative diagnosis is difficult, the diagnosis can only rely on the histopathological results and immunohistochemical results. It is very easy to be confused with other malignant tumors of the ovary and miss the best treatment time and delay the disease. We report a case of ovarian DLBCL in our hospital, in which the patient presented with the main complaint of abdominal distension and without other discomfort, and the atypical imaging examination. The patient was initially diagnosed as a pelvic mass after admission. The diagnosis was confirmed by exploratory laparotomy, and surgery and chemical treatment were given. Now we retrospectively analyze the clinical data of the patient and review the relevant literature to deepen the clinicians′ understanding of this disease and effectively improve the clinical diagnosis and treatment.

Key words: Ovarian neoplasms, Lymphoma, large B-cell, diffuse, Lymphoma, Diagnosis, Therapy, Case reports

王敏, 李佳慧, 崔君泽, 周海燕, 郭冉冉, 马帅. 卵巢原发性弥漫大B细胞淋巴瘤一例并文献复习[J]. 国际妇产科学杂志, 2023, 50(1): 43-46.

WANG Min, LI Jia-hui, CUI Jun-ze, ZHOU Hai-yan, GUO Ran-ran, MA Shuai. Primary Diffuse Large B Cell Lymphoma of Ovary: A Case Report and Literature Review[J]. Journal of International Obstetrics and Gynecology, 2023, 50(1): 43-46.

图/表 1

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