妊娠合并库肯勃瘤的诊疗进展

doi:10.12280/gjfckx.20240516

摘要/Abstract

摘要：

库肯勃瘤（Krukenberg瘤）是指从原发部位转移至卵巢的卵巢恶性肿瘤，发病率不高，而妊娠合并Krukenberg瘤在临床上更为罕见，往往预后较差。多数患者早期临床表现不明显，很容易被妊娠期间的生理和激素变化所掩盖，造成早期诊断困难，诊断延迟，错失最佳治疗时间。迄今为止，关于妊娠合并Krukenburg瘤的诊断、治疗尚未达成共识，根据国内外研究表明，需根据临床表现、影像学检查等方法确诊，其治疗方案应个体化，根据患者的病情、孕周、母儿情况等决定。因此，对这种罕见疾病需进行更多的研究，提供有关早期发现、诊断和治疗方法的建议。综述妊娠合并Krukenberg瘤的诊疗进展，为临床诊疗提供一定的参考价值。

关键词: 妊娠, Krukenberg瘤, 卵巢肿瘤, 诊断, 治疗

Abstract:

Krukenburg tumor refers to an ovarian malignancy that metastasizes from a primary site, and its incidence is relatively low. Pregnancy complicated by Krukenberg tumor is even rarer in clinical practice, often associated with a poor prognosis. Most patients exhibit nonspecific early clinical symptoms, which are easily masked by physiological and hormonal changes during pregnancy, making early diagnosis challenging, leading to delayed diagnosis and missed optimal treatment timing. To date, there is no consensus on the diagnosis and treatment of pregnancy complicated by Krukenburg tumor. According to domestic and international studies, diagnosis should be confirmed based on clinical manifestations and imaging examinations, treatment should be individualized according to the patient′s condition, gestational age, maternal-fetal status. Therefore, more research is needed on this rare disease to provide recommendations for early detection, diagnosis and treatment methods. This review summarizes the progress in the diagnosis and treatment of Krukenberg tumor during pregnancy, providing a valuable reference for clinical practice.

Key words: Pregnancy, Krukenberg tumor, Ovarian neoplasms, Diagnosis, Therapy

黄沫雅, 赵雅倩, 何银芳. 妊娠合并库肯勃瘤的诊疗进展[J]. 国际妇产科学杂志, 2024, 51(5): 531-535.

HUANG Mo-ya, ZHAO Ya-qian, HE Yin-fang. Progress in the Diagnosis and Treatment of Pregnancy Complicated by Krukenberg Tumor[J]. Journal of International Obstetrics and Gynecology, 2024, 51(5): 531-535.

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