关键词: RNA, 未翻译, 子宫内膜肿瘤, 诊断, 治疗, 长链非编码RNA

Abstract:   Long non-coding RNA (lncRNA) plays an extremely important role of regulation in many pathophysiological processes of organism, whose dysfunction is much related to the development and progression of tumors. It has become a research hotspot of many disease mechanisms recently due to its large number, variety and polytropic function. Endometrial carcinoma is one of the most common malignant tumors in female reproductive system, which has much relation with lncRNA. The research of lncRNA in endometrial carcinoma is becoming more and more. With the progressing of techniques and methods of the research, it will help reveal the development and progression of endometrial carcinoma to explore the regulation mechanism of lncRNA to endometrial carcinoma. It can also provide a new pathway to the primary diagnosis and treatment of this disease, and is likely to become a novel marker related to prognosis or a target of drug treatment. This article will summarize the research progression of lncRNA in endometrial carcinoma.

Key words: RNA, untranslated, Endometrial neoplasms, Diagnosis, Therapy, Long non-coding RNA