关键词: 妊娠合并子宫颈癌, 宫颈肿瘤, 妊娠并发症, 肿瘤, 治疗, 期待治疗, 手术治疗, 新辅助化疗, 顺铂

Abstract: As the age of pregnancy grows, the rate of cervical cancer during pregnancy is increasing and the management of cervical cancer during pregnancy is also becoming more difficult in clinic. During treatment, safety of both pregnant women and offspring should be taken into account. Management of patients wishing to preserve of her pregnancy aim at fewer adverse effects on fetuses, less tumor progress and similar outcomes with non-pregnancy women with cervical cancer. Current options to treat pregnant patients with cervical cancer desired to preserve pregnancy contains expectant treatment, surgery and chemotherapy. Radical trachelectomy, simple trachelectomy and conization are common surgical methods and most common chemotherapy is based on platinum，with or without other agents. Commonly, patients with stage ⅠA1 cervical cancer are eligible for expectant treatment. Surgical treatment is option for patients with stage ⅠA2-ⅠB1 cervical cancer and neoadjuvant chemotherapy is used in patients with stage ⅠB1 or greater cervical cancer. Patients with lymph nodes metastasis should terminate pregnancy. We will make conclusions on the latest progression of pregnancy-preserving managements.

Key words: Cervical cancer in pregnancy, Uterine cervical neoplasms, Pregnancy complications, neoplastic, Therapy, Expectant treatment, Surgical treatment, Neoadjuvant chemotherapy, Cisplatin