完全型雄激素不敏感综合征合并无性细胞瘤一例

doi:10.12280/gjfckx.20240083

国际妇产科学杂志 ›› 2024, Vol. 51 ›› Issue (4): 392-394.doi: 10.12280/gjfckx.20240083

• 妇科肿瘤研究: 病例报告 • 上一篇下一篇

完全型雄激素不敏感综合征合并无性细胞瘤一例

尹雨鑫, 王长河()

272013 山东省济宁市，济宁医学院临床医学院（尹雨鑫）；济宁市第一人民医院（王长河）

收稿日期:2024-01-22 出版日期:2024-08-15 发布日期:2024-07-25
通讯作者: 王长河，E-mail：changhe2825701@sina.com

A Case Report of Complete Androgen Insensitivity Syndrome Complicated with Dysgerminoma

YIN Yu-xin, WANG Chang-he()

School of Clinical Medicine, Jining Medical University, Jining 272013, Shandong Province, China (YIN Yu-xin); Jining First People's Hospital, Jining 272011, Shandong Province, China (WANG Chang-he)

Received:2024-01-22 Published:2024-08-15 Online:2024-07-25
Contact: WANG Chang-he, E-mail: changhe2825701@sina.com

摘要/Abstract

摘要：

雄激素不敏感综合征（androgen insensitivity syndrome，AIS）临床较为罕见，早期诊断困难。报告1例完全型雄激素不敏感综合征（complete androgen insensitivity syndrome，CAIS）合并无性细胞瘤患者的诊治经过，患者因腹胀2 d，门诊行彩色超声提示盆腔肿物收入院，入院后先行盆腔肿物切除术治疗，因术前高雄激素血症原因不明，经染色体分析及基因检测最终明确诊断为CAIS合并无性细胞瘤，并最终行性腺恶性肿瘤根治术。目前该患者仍在密切随访中，病情稳定。通过回顾性分析该病例的临床特点及诊治经过，以期提高临床对于该病的认识。

关键词: 雄激素迟钝综合征, 性发育障碍, 无性细胞瘤, 雄激素增多症, 病例报告

Abstract:

Androgen insensitivity syndrome (AIS) is rare and difficult to diagnose at an early stage. This paper reports the diagnosis and treatment of a patient with complete androgen insensitivity syndrome (CAIS) complicated with dysgerminoma. The patient was admitted to the hospital due to abdominal distension for 2 days and received color ultrasound in the outpatient department indicating pelvic tumor. After admission, pelvic tumor resection was performed. Since the cause of hyperandrogenemia was unknown before surgery, it was diagnosed as CAIS complicated with dysgerminoma by chromosome analysis and genetic testing, finally underwent radical resection of gonadal malignant tumor. At present, the patient is still under close follow-up and his condition is stable. Through retrospective analysis of the clinical characteristics and diagnosis and treatment of this case, in order to improve the clinical understanding of the disease.

Key words: Androgen-insensitivity syndrome, Disorders of sex development, Dysgerminoma, Hyperandrogenism, Case reports

尹雨鑫, 王长河. 完全型雄激素不敏感综合征合并无性细胞瘤一例[J]. 国际妇产科学杂志, 2024, 51(4): 392-394.

YIN Yu-xin, WANG Chang-he. A Case Report of Complete Androgen Insensitivity Syndrome Complicated with Dysgerminoma[J]. Journal of International Obstetrics and Gynecology, 2024, 51(4): 392-394.

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完全型雄激素不敏感综合征合并无性细胞瘤一例

A Case Report of Complete Androgen Insensitivity Syndrome Complicated with Dysgerminoma

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