国际妇产科学杂志 ›› 2017, Vol. 44 ›› Issue (1): 71-74.

• 综述 • 上一篇    下一篇

脑胎盘率诊断胎儿宫内缺氧的研究进展

郭琳娜,张志坤   

  1. 天津市中心妇产科医院
  • 收稿日期:2016-09-23 修回日期:2016-11-01 出版日期:2017-02-15 发布日期:2017-03-28
  • 通讯作者: 郭琳娜 E-mail:goudianzi@163.com
  • 基金资助:
    天津市卫生局科技基金

Research Progress of Cerebroplacental Ratio Used in Diagnosis of Fetal Intrauterine Anoxia

  • Received:2016-09-23 Revised:2016-11-01 Published:2017-02-15 Online:2017-03-28

摘要: 胎儿宫内缺氧是围生儿死亡的重要原因之一,产前有效预测胎儿宫内缺氧,对降低围生儿死亡率具有重大意义。联合检测胎儿各项多普勒血流参数,包括脐动脉、大脑中动脉、肾动脉、静脉导管、腹内脐静脉等,反映胎儿各个器官的异常状态,能准确地评价胎儿宫内缺氧状况,提高胎儿窘迫的诊断率。脑胎盘率利用大脑中动脉与脐动脉搏动指数的比值,消除了共同的干扰因素,排除了基数波动的影响,受血流灌注阻抗变化的影响小,比单一血管更能反映胎儿全身血流分布情况,用于早期评价胎盘胎儿血流循环变化,从而更全面地评价宫内缺氧程度,早期预测妊娠不良结局,及时快速准确的发现异常,及时干预,提高围生儿质量,具有临床应用价值,值得在临床推广应用。

关键词: 脑, 胎盘, 超声检查, 多普勒, 胎儿, 胎儿窘迫

Abstract: Fetal intrauterine anoxia is one of the important causes of perinatal death. Prenatal fetal hypoxia can be effectively predicted, it is great significance to reduce perinatal mortality. Combined detection of fetal doppler blood flow parameters,including the umbilical artery, middle cerebral artery, renal artery, venous catheter, abdominal umbilical vein, reflect the abnormal state of fetal organs, can accurately assess fetal intrauterine hypoxia status, to improve the diagnostic rate of fetal distress. The ratio of cerebral artery and umbilical artery pulsation index was used to eliminate the common interference factors, which ruled out the influence of the base fluctuation, and was affected by the change of blood perfusion impedance. Cerebroplacental rate can reflect the distribution of blood flow of fetal body more than a single vessel, for early evaluation of placenta fetal blood circulation changes, thus a more comprehensive evaluation of intrauterine hypoxia degree, predict adverse outcomes of pregnancy earlier, timely detect the abnormal, timely intervention, improve the perinatal quality, have more clinical value, it is worth to be popularized in clinical application.

Key words: Brain, Placenta, Ultrasonography, Doppler, color, Fetus, Fetal distress