国际妇产科学杂志 ›› 2018, Vol. 45 ›› Issue (5): 515-522.

• 综述 • 上一篇    下一篇

评分系统在评价卵巢癌瘤体减灭术满意度和预后中的价值

张月如,冯炜炜   

  1. 200001 上海交通大学附属瑞金医院妇产科
  • 收稿日期:2018-05-16 修回日期:2018-08-13 出版日期:2018-10-15 发布日期:2018-10-18
  • 通讯作者: 冯炜炜,E-mail:wfeng7347@aliyun.com E-mail:wfeng7347@aliyun.com
  • 基金资助:
    上海交通大学医学院高峰高源计划——“研究型医师”项目(20172003)

Different Scoring Methods in Predicting Respectability and Prognosis in Advanced Ovarian Cancer

ZHANG Yue-ru,FENG Wei-wei   

  1. Ruijin Hospital Affiliated to Shanghai Jiao Tong University,Shanghai 200001,China
  • Received:2018-05-16 Revised:2018-08-13 Published:2018-10-15 Online:2018-10-18
  • Contact: FENG Wei-wei, E-mail:wfeng7347@aliyun.com E-mail:wfeng7347@aliyun.com

摘要: 目前晚期卵巢癌的常规治疗方案为:初始瘤体减灭术+术后铂类为主的化疗;或者先行探查术或穿刺确诊,行新辅助化疗,再行中间减瘤术。两种方案的选择主要基于患者的肿瘤负荷,还受行减瘤术后发生术后并发症风险的影响。有很多学者提出了相应的评分预测系统,旨在术前或术中评估卵巢癌患者的肿瘤负荷、手术并发症风险来判断其能否行初始满意减瘤术及其预后;目前使用较普遍的评分系统主要有Fagotti评分、改良Fagotti评分(Fagotti-modified评分)、CT评分、Aletti评分、并发症评分、PCI评分以及其他评分系统。Fagotti评分及改良Fagotti评分是腹腔镜探查评分系统,主要用于预测能否行满意减瘤术;CT评分主要用CT检查结合临床特征对是否能行满意肿瘤减灭术进行术前预测;Aletti评分主要描述手术复杂程度;并发症评分主要用于描述手术后并发症发生的风险;PCI评分主要是用于评价肿瘤的腹膜盆腔扩散程度,其他还包括Anne-Lucie Dessapt提出的R0预测评分模型以及Eisenkop提出的五分区评分。

关键词: 卵巢肿瘤, 抗肿瘤联合化疗方案, 腹腔镜, 预测

Abstract: Routine therapies for advanced ovarian cancer are as the followings: primary cytoreductive surgery+ platinum based chemotherapy, pathologic  diagnoses by laparoscopy or puncture biopsy,then doing neoadjuvant chemotherapy and interval debulking surgery. Whether to perform a primary cytoreductive surgery is determined by the patient’s tumor load and the risk of postoperative complications which several scoring systems have been developed to predict.We have several predictive scoring systems: Fagotti score, Fagotti-modified score, CT score, Aletti score, PCI score and other scoring systems. Both Fagotti score and Fagotti-modified score under laparoscopy are used to see the probability of optimal cytoreductive surgery. CT score is combined with clinical characteristics to decide whether to perform a primary debulking surgery. Aletti score describes the complexity of a surgery. We also have a score system to predict  postoperative complications. PCI score uses to evaluate tumor load of pelvic cavity and peritoneum. Besides, Anne-Lucie Dessapt presented a R0 prediction model and Eisenkop proposed a five-region prediction model.

Key words: Ovarian neoplasms, Antineoplastic combined chemotherapy protocols, Laparoscopes, Forecasting

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