国际妇产科学杂志 ›› 2019, Vol. 46 ›› Issue (3): 249-252.

• 综述 • 上一篇    下一篇

子宫肉瘤研究进展

陶胜男,周颖,孙金,叶桂萍,胡来花,胡卫平   

  1. 230000 合肥,安徽医科大学附属省立医院妇产科
  • 收稿日期:2018-11-21 修回日期:2019-02-01 出版日期:2019-06-15 发布日期:2019-06-25
  • 通讯作者: 胡卫平,E-mail:syhwp@163.com E-mail:syhwp@163.com

Progress in Research on Uterine Sarcoma

TAO Sheng-nan,ZHOU Ying,SUN Jin,YE Gui-ping,HU Lai-hua,HU Wei-ping   

  1. Department of Obstetrics and Gynecology,Anhui Provincial Hospital Affiliated to Anhui Medical University,Hefei 230000,China
  • Received:2018-11-21 Revised:2019-02-01 Published:2019-06-15 Online:2019-06-25
  • Contact: HU Wei-ping,E-mail:syhwp@163.com E-mail:syhwp@163.com

摘要: 子宫肉瘤是发生于女性生殖器官的恶性肿瘤,其发病率低、预后差,主要有异常阴道出血、腹痛、腹部包块等临床表现。血清乳酸脱氢酶、血清中性粒细胞与淋巴细胞比值(NLR)等血清学指标及超声和磁共振成像等影像学检查可协助子宫肉瘤的术前诊断,但目前其诊断仍主要依靠术后病理结果。子宫肉瘤主要有子宫平滑肌肉瘤、子宫内膜间质肉瘤及子宫腺肉瘤3种病理类型。全子宫及双附件切除是标准手术方式,术后可根据不同病理类型及手术分期选择辅助治疗方式。通过查阅国内外文献,综述子宫肉瘤的临床表现、辅助检查、病理特征、治疗及预后等。

关键词: 子宫肉瘤, 子宫肿瘤, 肉瘤, 诊断, 治疗, 预后, 子宫平滑肌肉瘤, 子宫内膜间质肉瘤, 子宫腺肉瘤

Abstract: Uterine sarcoma is a malignant tumor that occurs in the female genital system. Its incidence is low and its prognosis is poor. Its manifestations mainly include abnormal vaginal bleeding, abdominal pain and abdominal mass. Serological indicators such as serum lactate dehydrogenase, serum neutrophil to lymphocyte ratio (NLR), and ultrasound and magnetic resonance examinations can assist in the preoperative diagnosis of uterine sarcoma, but the diagnosis still depends on postoperative pathology. Uterine sarcomas include three pathological types: uterine leiomyosarcoma, endometrial stromal sarcoma and uterine adenosarcoma. Whole uterus and double attachment resection are standard surgical methods, and adjuvant treatment can be selected according to different pathological types and surgical stages. This article summarizes the clinical manifestations, auxiliary examinations, pathological features, treatment and prognosis of uterine sarcoma by consulting domestic and foreign literature.

Key words: Uterine sarcoma, Uterine neoplasms, Sarcoma;Diagnosis, Therapy, Prognosis, Uterine leiomyosarcoma, Endometrial stromal sarcoma, Uterine adenosarcoma