国际妇产科学杂志 ›› 2019, Vol. 46 ›› Issue (5): 560-563.

• 综述 • 上一篇    下一篇

子宫浆液性癌治疗现状与进展

张傢钧,王晓慧   

  1. 730000 兰州大学第一临床医学院,兰州大学第一医院妇产科,甘肃省妇科肿瘤重点实验室
  • 收稿日期:2019-04-29 修回日期:2019-05-22 出版日期:2019-10-15 发布日期:2019-10-21
  • 通讯作者: 王晓慧,E-mail:xiaohuiwang2015@163.com E-mail:xiaohuiwang2015@163.com
  • 基金资助:
     

Current Status and Progress in the Treatment of Uterine Serous Carcinoma

ZHANG Jia-jun, WANG Xiao-hui   

  1. The First Clinical Medical College of Lanzhou University,Department of Obstetrics and Gynecology,The First Hospital of Lanzhou University,Gansu Province Key Laboratoy of Gynecological Oncology,Lanzhou 730000,China
  • Received:2019-04-29 Revised:2019-05-22 Published:2019-10-15 Online:2019-10-21
  • Contact: WANG Xiao-hui,E-mail:xiaohuiwang2015@163.com E-mail:xiaohuiwang2015@163.com
  • Supported by:
     

摘要: 子宫浆液性癌[USC,又称子宫乳头状浆液性癌(UPSC)]是一种Ⅱ型子宫内膜癌的特殊病理类型,具有侵袭性强、术后复发率高、易发生远处转移和预后较差等特点。由于该病发病率较低,缺少前瞻性随机对照试验,近年多篇大数据回顾分析结果结合美国国立综合癌症网络(NCCN)对USC的治疗建议,推荐全面分期手术,术后辅以化疗、放疗、分子靶向治疗、免疫疗法等综合治疗。目前,关于USC的最佳治疗方案尚未达成共识。现就USC相关治疗现状和进展进行阐述,希望对临床治疗有一定的帮助。

关键词: 子宫内膜肿瘤, 外科手术, 抗肿瘤联合化疗方案, 放射疗法, 免疫疗法

Abstract: Uterine Serous Carcinoma [USC, also known as uterine papillary serous carcinoma (UPSC)] is a special pathological type of type Ⅱ endometrial cancer, with the characteristics of strong invasiveness, high postoperative recurrence rate, prone to distant metastasis, poor prognosis and so on. Because of its low incidence and lack of prospective randomized controlled trials, combining with the treatment recommendations of the National Comprehensive Cancer Network (NCCN) for USC in recent years, it is recommended that USC be treated by comprehensive staged surgery, combined with chemotherapy, radiotherapy, molecular targeted therapy and immunotherapy. At present, there is no consensus on the best treatment for uterine serous cancer. Now I will elaborate on the current status and progress of the treatment of uterine serous carcinoma related treatment, and hope to be helpful for clinical treatment.

Key words: Endometrial neoplasms, Surgical procedures, operative, Antineoplastic combined chemotherapy protocols, Radiotherapy, Immunotherapy

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