国际妇产科学杂志

国际妇产科学杂志 ›› 2011, Vol. 38 ›› Issue (3): 227-230.

• 综述 • 上一篇    下一篇

MRKH综合征及其手术治疗的研究现状

符庆瑞,史惠蓉,纪 妹   

  1. 450052 郑州大学第一附属医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-06-15 发布日期:2011-06-15
  • 通讯作者: 史惠蓉

MRKH Syndrome and Current Development of Vaginoplasty

FU Qing -rui，SHI Hui-rong，JI Mei   

  1. Department of Gynecology and Obstetrics，the First Affiliated Hospital of Zhengzhou University， Zhengzhou 450052，Chin
  • Received:1900-01-01 Revised:1900-01-01 Published:2011-06-15 Online:2011-06-15
  • Contact: 史惠蓉

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摘要： 先天性子宫阴道缺如（Mayer-Rokitansky-Küster-Hauser，MRKH）综合征的发生可能与多种基因有关，并有家族遗传性及聚集性。该病的主要治疗方法是人工阴道成形术。随着腹腔镜技术和组织工程技术的应用和发展，研究者均尝试着对手术方式进行改进和创新，并对患者进行长期随访以评价各种术式的治疗效果。综述MRKH综合征的病因和主要手术治疗方式及随访评价结果。

关键词: 阴道, 腹腔镜, 组织工程, 随访研究, 治疗, MRKH综合征

Abstract: The hypothesis of polygenic/multifactorial causes for MRKH syndrome（congenital utero-vaginal aplasia） has been reinforced，as well as familial heredity and aggregation. Vaginoplasty is the main treatment method. With the application and improvement of laparoscopic operation and tissue engineering technique，researchers have been trying to continuously develop and innovate vaginoplasty，then evaluate the effectiveness of different procedure by long-term follow-up. The article below will overview the causes，the main methods of operation of MRKH and their follow-up results.

Key words: Vagina, Laparoscopes, Tissue engineering, Follow-up studies, Therapy, MRKH syndrome