国际妇产科学杂志

国际妇产科学杂志 ›› 2010, Vol. 37 ›› Issue (6): 427-429.

• 综述 • 上一篇    下一篇

PET和PET/CT在宫颈癌中的应用

程 煜 ，鹿 欣   

  1. 200011 上海，复旦大学附属妇产科医院
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-12-15 发布日期:2010-12-15
  • 通讯作者: 鹿 欣

Application of PET and PET/CT in Cervical Cancer

CHENG Yu，LU Xin   

  1. The Obstetrics and Gynecology Hospital of Fudan University，Shanghai 200011，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2010-12-15 Online:2010-12-15
  • Contact: LU Xin

PDF (PC)

4783

摘要： 宫颈癌是女性最常见的恶性肿瘤之一。正电子发射断层显像（positron emission tomography，PET）及PET/CT能够同时提供肿瘤的解剖结构和代谢图像，不受局部解剖位置改变的影响，具有较高的特异度，并且能够通过18-氟代脱氧葡萄糖（18F-FDG）标准摄取值辅助评估肿瘤转移的可能性，因此其对宫颈癌患者淋巴结和远处转移的检查效果优于传统的影像学检查，并且有助于早期发现复发肿瘤、评估预后和制定治疗方案。但18F-FDG标准摄取值的临床使用价值、PET及PET/CT检查能否代替传统的检查方式或临床分期还需大样本前瞻性研究证实。

关键词: 宫颈肿瘤, 正电子发射断层显像术, 预后, 体层摄影术, 螺旋计算机, 磁共振成像

Abstract: Cervical cancer is one of the most common malignancies in women. PET and PET/CT offer the combined anatomic and functional imaging， have high specificity for detecting tumor or metastasis lesions，and have been used to localize areas of standard fluoro-2-deoxy-D-glucose（FDG） uptake value（SUV） and help to assess the metastatic potential without impact of anatomic change after surgery. Therefore， PET and PET/CT have more advantages than traditional radiologic examinations in detecting lymph node and distant metastasis in patients with cervical cancer and are useful to identify recurrent cervical cancer， evaluate the prognosis and make the treatment plan. However， a larger prospective study is still needed to confirm the effectiveness of SUV in clinical practice and whether PET and PET/CT can take the place of other imaging methods and clinical staging procedures.

Key words: Cervical neoplasms, Positron-emission tomography, Prognosis, Tomography, spiral computed, Magnetic resonance imaging