国际妇产科学杂志

国际妇产科学杂志 ›› 2025, Vol. 52 ›› Issue (4): 447-450.doi: 10.12280/gjfckx.20250222

• 妇科肿瘤研究:病例报告 • 上一篇    下一篇

原发性输卵管癌肉瘤伴广泛网膜转移一例

张世霞, 闫宇, 万子华, 刘畅()   

  1. 730000 兰州大学第一临床医学院（张世霞，闫宇，万子华）； 兰州大学第一医院妇产科，甘肃省妇科肿瘤重点实验室（刘畅）
  • 收稿日期:2025-03-06 出版日期:2025-08-15 发布日期:2025-09-08
  • 通讯作者: 刘畅，E-mail：lch@lzu.edu.cn

A Case Report of Primary Fallopian Tube Carcinosarcoma with Extensive Omental Metastasis

ZHANG Shi-xia, YAN Yu, WAN Zi-hua, LIU Chang()   

  1. The First School of Clinical Medicine of Lanzhou University, Lanzhou 730000, China (ZHANG Shi-xia, YAN Yu, WAN Zi-hua); Department of Obstetrics and Gynecology, The First Hospital of Lanzhou University, Gansu Province Key Laboratory of Gynecological Oncology, Lanzhou 730000, China (LIU Chang)
  • Received:2025-03-06 Published:2025-08-15 Online:2025-09-08
  • Contact: LIU Chang, E-mail: lch@lzu.edu.cn

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摘要：

原发性输卵管癌肉瘤是起源于中胚叶组织的恶性肿瘤，极少见。其病因及发病机制尚不明确，临床以手术治疗为主。现报告1例原发性输卵管癌肉瘤伴广泛网膜转移的病例。患者因腹痛行盆腔磁共振成像，发现盆腔一巨大实性肿物，伴双侧髂血管及腹主动脉旁淋巴结肿大，经多学科讨论后行经腹盆腔肿物切除术+全子宫切除术+大网膜阑尾切除术+盆腔淋巴结清扫术及肿瘤细胞减灭术。术后给予紫杉醇联合卡铂静脉化疗1个周期，患者因化疗后骨髓抑制无法耐受，签字离院，电话随访已离世。结合此病例总结输卵管癌肉瘤的发病特点、组织病理表现、诊断、治疗及预后，旨在提高临床医师对该类疾病的认识，为其临床诊治提供参考。

关键词: 输卵管, 癌肉瘤, 诊断, 治疗, 病例报告

Abstract:

Primary carcinosarcoma of the fallopian tube is a rare malignant tumor originating from mesodermal tissues. Its etiology and pathogenesis remains unclear, and surgical treatment is the main clinical approach. We report a case of primary carcinosarcoma of the fallopian tube with extensive omental metastasis. The patient underwent pelvic magnetic resonance imaging because of abdominal pain, which revealed a large solid pelvic mass accompanied by enlarged bilateral iliac vessels and para-aortic lymph nodes. After multi-disciplinary discussion, the patient underwent transabdominal pelvic mass resection, total hysterectomy, omentectomy and appendectomy, pelvic lymph node dissection, and tumour cytoreduction surgery. After the operation, the patient received one cycle of intravenous chemotherapy with paclitaxel combined with carboplatin. Due to intolerable myelosuppression after chemotherapy, the patient signed out of the hospital and passed away according to telephone follow-up. By summarizing the onset characteristics, histopathological manifestations, diagnosis, treatment and prognosis of tubal carcinosarcoma in this case, we aim to improve clinicians′understanding of this disease and provide references for its clinical diagnosis and treatment.

Key words: Fallopian tubes, Carcinosarcoma, Diagnosis, Therapy, Case reports