Research Progress of MicroRNA in Endometriosis

doi:10.12280/gjfckx.20200903

Abstract

Abstract:

Endometriosis(EMs) is a highly recurrent and invasive benign disease, which seriously affects the quality of life of female between puberty and menopause. The lack of effective biomarkers in clinic is one of the important causes leading to the delay of diagnosis. With the progress of the disease, it brings serious health damage and economic burden to patients. At present, laparoscopy is the method for the diagnosis of EMs, but its application in clinic is limited because of its invasiveness, operative complications and high cost. The exploration of biomarkers with good sensitivity and specificity is very important for the non-invasive early diagnosis of EMs. MicroRNA (miRNA) is a kind of non-coding small molecule RNA, with high tissue specificity and stability. Recent studies have shown that miRNA can be used as a potential biomarker for the diagnosis of EMs. Early recognition is helpful for timely diagnosis and treatment of patients. This article reviews the research progress of miRNA in EMs.

Key words: Endometriosis, MicroRNAs, Biomarkers,pharmacological, Infertility,female, Serum, Plasma

HONG Ya-yi, TANG Xiao-han, LU Mei-song. Research Progress of MicroRNA in Endometriosis[J]. Journal of International Obstetrics and Gynecology, 2021, 48(3): 277-280.

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