Journal of International Obstetrics and Gynecology ›› 2021, Vol. 48 ›› Issue (5): 560-562.doi: 10.12280/gjfckx.20201202

• Research on Gynecological Malignancies: Case Report • Previous Articles     Next Articles

Mesonephric Adenocarcinoma of the Uterus Corpus: A Case Report and Literature Review

ZHANG Fang-yuan, LIU Zi-wei, CHEN Yu-ying, JIA Yan()   

  1. Department of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun 130041, China
  • Received:2020-12-18 Published:2021-10-15 Online:2021-10-27
  • Contact: JIA Yan E-mail:jiayan@jlu.edu.cn

Abstract:

Mesonephric adenocarcinoma is a rare malignant tumor with a low incidence. It originates from mesonephric remnants or its hyperplasia, which often lies in cervix and rarely remains in the uterus corpus. Mesonephric adenocarcinoma of the uterus corpus(UCMA) is lack of special clinical presentation, which often presents with vaginal bleeding, thus leading to the diagnosis of genital tract inflammation, uterine fibroids, cervical cancer, endometrial cancer and so on. Cytology, pathology, immunohistochemistry and molecular character are required to get accurate diagnosis. According to recent reports, GATA3 is regarded as its special marker. In addition, the prognosis of UCMA is poor, and its treatment options include surgery and adjuvant radiotherapy and chemotherapy. This paper reports a case of UCMA that was misdiagnosed as uterine fibroids before surgery, reviews the relevant literature and summarized the clinical features in order to reduce its misdiagnosis and get awareness raised.

Key words: Uterine neoplasms, Adenocarcinoma, Uterine hemorrhage, Diagnosis, Therapy, Case reports