Abstract:

Mesonephric-like adenocarcinoma of the ovary is a kind of adenocarcinoma presenting as mesonephric-like differentiation. The origin of mesonephric-like adenocarcinoma is uncertain, and the related reports at home and abroad are few. There are no relevant guidelines for diagnosis and treatment of this disease. A 67-year-old woman with bilateral solid ovarian cyst and highly suspected malignant ovarian tumor was treated by operation, the postoperative pathological diagnosis was bilateral ovarian mesonephric-like adenocarcinoma with borderline serous mucinous tumor. The clinical manifestations of the disease were nonspecific. Its pathological immunohistochemistry was characterized by negative ER and PR, GATA3 and TTF-1 expression. Due to the lack of specific postoperative diagnosis and therapeutic criteria for this disease, the postoperative chemotherapy regimen of paclitaxel plus carboplatin for 6 courses was proposed. The analysis of this case was intended to provide more reference for diagnosis and treatment of this disease for subsequent studies.

Key words: Mesonephroma, Ovarian neoplasms, Adenocarcinoma,mucinous, Diagnosis, Therapy, Prognosis, Case reports, Mesonephric-like adenocarcinoma