Abstract:

Uterine fibroids can lead to abnormal uterine bleeding, frequent urination or constipation, infertility and other symptoms, affecting the physical and mental health of patients. High-intensity focused ultrasound (HIFU) is a technology that promotes the necrosis of target tissue by focusing low-energy ultrasound in vitro, which can significantly reduce the volume of uterine fibroids and improve the clinical symptoms of patients. It has become an important method for the treatment of uterine fibroids. As a kind of treatment of uterine fibroids, HIFU has the advantage of non-invasive and retaining the structural integrity of the uterus, which can be safely used in patients with uterine fibroids with fertility requirements and shorten the time of contraception after treatment. However, the long-term reintervention rate after HIFU treatment of uterine fibroids is high, and HIFU may increase the incidence of some pregnancy complications such as preterm birth and fetal growth restriction. There is no complete solution to the exclusion of malignant diseases such as uterine sarcoma before HIFU treatment. In this review, we summarize the research progress of HIFU treatment of uterine fibroids in recent years, so as to provide reference for clinical treatment of uterine fibroids.

Key words: High-intensity focused ultrasound ablation, Uterine neoplasms, Leiomyoma, Treatment outcome, Pregnancy