Journal of International Obstetrics and Gynecology ›› 2023, Vol. 50 ›› Issue (2): 234-236.doi: 10.12280/gjfckx.20220374

• Research on Gynecological Malignancies: Case Report • Previous Articles     Next Articles

Rhabdomyolysis after Laparoscopic Surgery for Cervical Cancer: A Case Report and Literature Review

LI Juan, XU Xiao-ying, SHENG Yan-nan, MA Fu-tang, ZHAO Ya-qin, WANG Fang, WU Zhen-zhen()   

  1. Gansu Provincial Maternity and Chid-Care Hospital, Lanzhou 730050, China (LI Juan, XU Xiao-ying, SHENG Yan-nan, MA Fu-tang, ZHAO Ya-qin, WANG Fang, WU Zhen-zhen); First School of Clinical Medical, Gansu University of Chinese Medicine, Lanzhou 730000, China (XU Xiao-ying, WU Zhen-zhen)
  • Received:2022-05-15 Published:2023-04-15 Online:2023-04-24
  • Contact: WU Zhen-zhen, E-mail: 2396530559@qq.com

Abstract:

Rhabdomyolysis (RM) is a well-known clinical syndrome caused by the breakdown and necrosis of muscle tissue. It can lead to electrolyte abnormalities and acute kidney injury. A case of RM is analyzed retrospectively during laparoscopic surgery for cervical cancer. It is related to the state of general anesthesia, surgical position and long time immobilization. It is characterized by muscle pain, weakness, and dark pigmentation of the urine. The diagnosis is confirmed by elevated creatine kinase and myoglobin levels. The management of RM is prompt intravenous volume expansion, maintainous urine output, and continuous renal replacement therapy (CRRT). Doctors need to pay attention to the intro-operative RM. Prolonged duration and passive position of surgery is a well-recognized risk factor in the development of RM. It emphasize the importance of placing the patient in the surgical position in the awake state.

Key words: Rhabdomyolysis, Acute kidney injury, Uterine cervical neoplasms, Gynecologic surgical procedures, Myoglobinuria