Journal of International Obstetrics and Gynecology ›› 2025, Vol. 52 ›› Issue (4): 377-383.doi: 10.12280/gjfckx.20250195

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Research Progress on the Relationship between Hypertensive Disorders of Pregnancy and Stillbirth

YAO Zheng-yang, WU Shao-wen, LIU Rui-xia, YIN Cheng-hong()   

  1. Central Laboratory (YAO Zheng-yang, LIU Rui-xia, YIN Cheng-hong), Department of Obstetrics and Gynecology (WU Shao-wen), Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China
  • Received:2025-02-28 Published:2025-08-15 Online:2025-09-08
  • Contact: YIN Cheng-hong, E-mail: yinchh@ccmu.edu.cn

Abstract:

Stillbirth is one of the severe complications of pregnancy. The occurrence of stillbirth not only brings huge psychological burdens and harm to pregnant women and their families but also imposes relatively large economic burden on society. Hypertensive disorders of pregnancy (HDP) are one of the common complications during pregnancy. Recent studies have shown that HDP is one of the important maternal factors leading to stillbirth. However, little is known about the influence of different hypertension classifications on HDP and stillbirth. The relationship between blood pressure control levels and stillbirth remains controversial, and there are also disputes about whether the use of drugs such as aspirin in the treatment of HDP in pregnant women is beneficial. This review summarizes the influence of HDP on stillbirth, the impact of drug treatment for HDP on stillbirth, the mechanism by which HDP leads to stillbirth, and the management of stillbirth caused by HDP, aiming to provide more scientific and accurate guidance for the prevention and management of stillbirth.

Key words: Pregnancy, Hypertension, Hypertension, pregnancy-induced, Fetal death, Therapy, Pregnancy management