Journal of International Obstetrics and Gynecology ›› 2010, Vol. 37 ›› Issue (4): 288-290.

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Use the Conventional Papanicolaou Smear by Improved Take-samples in Screening Cervical Carcinoma in People

WANG Guo-ping,LI Rui-zhen,WU Lan-na,LI Juan,LIU Zhi-hong,WANG Chun,HE Fang,ZHOU Yan- qiu,WENG Lei-ming,WU Rui-fang   

  1. Centre of Early Diagnosis and Early Treatment for Cervical Carcinoma,Peking University Shenzhen Hospital, Shenzhen 518036,China
  • Received:1900-01-01 Revised:1900-01-01 Published:2010-08-15 Online:2010-08-15
  • Contact: WU Rui-fang

Abstract: Objective:To investigate the value of conventional Papanicolaou smear (Pap) improved by take-samples in screening cervical carcinoma. Methods: Conventional Pap smear by improved take-samples, liquid-based cytology test, hybrid capture Ⅱ human papillomavarus test were performed in 500 women of 30-59 years old without screening cervical cancer in 3 years in Shang Mei-lin community of Shenzhen Futian region from December 2007 to March 2008. We obtained samples of Pap by a broom-type sampling device(take-samples used for LCT) with split-sampling method. The positive threhold of cervical cytology was atypical squamous cells of undetermined sign(ASCUS). The women with either testing result of Pap,LCT or HPV positive received multi-spot biopsy under colposcopy. The pathology results were the final diagnosis criteria to evaluate the value of two cervical cytology for screening cervical cancer. Results:The best screening cervical intraepithelial neoplasia (CIN)Ⅱ threhold of cervical cytology was ASCUS;There were no significant differences of screening effectiveness and unsatisfactory rate between Pap with improved take-samples and LCT; The complete concordance of diagnosis between Pap and LCT was 86.8%,The higher grade cervical lesion,the better concordance of diagnosis between Pap and LCT. Conclusions:Pap smear with improved take-samples is economic and effective and is worth popularizing in screening cervical carcinoma.

Key words: Uterine cervical neoplasms, Vaginal smears, Staining and labeling, Mass screening, Cytology