Abstract: Myasthenia gravis （MG） is an autoimmune disease of the neuromuscular junction characterized by skeletal muscle weakness. The course of MG during pregnancy is unpredictable. The stage and medication of MG will have effects on fetus，neonate and long-term outcome of the offspring. There will be an interaction between MG and pregnancy，partum，anaesthesia. The patients should be given individual regimen during pregnancy. If well-controlled，the patient will undergo caesarean section only with obstetric indication. The duration should be shortened by forceps when vaginal delivery. Strict surveillance and therapeutic regimen are crucial to the pregnant women with MG. This article reviews the advances on clinical research in pregnancy complicated with MG.

Key words: Pregn, Myasthenia gravis, Perinatal care, Therapy