Abstract: Objective： To study the clinical features，selection of operation methods and prognosis of vulvar squamous cell carcinomas. Methods：59 patients with vulvar squamous carcinoma for surgical treatment from February 2006 to October 2012 in Shengjing Hospital Affiliated to China Medical University were retrospectively analyzed. Results：59 patients of survival difference with different pathological stages and clinical stages was statistically significant difference，ⅠA best prognosis in patients with; In different ages，the worst prognosis was the onset age less than 45. Different ways of operation in patients with follow-up survival rate difference was statistically significant. Conclusions：The prognosis of vulvar squamous cell carcinomas were relate age，tumor site，tumor infiltration depth and size，pathological type，operation method and postoperative adjuvant radiation and chemotherapy，and individualized treatment should be considered.

Key words: Vulvar neoplasms, Neoplasms, squamous cell, Prognosis