Journal of International Obstetrics and Gynecology ›› 2026, Vol. 53 ›› Issue (2): 228-232.doi: 10.12280/gjfckx.20251118

• Research on Gynecological Malignancies: Case Report • Previous Articles     Next Articles

A Case of Malignant Solitary Fibrous Tumor in the Pelvic Retroperitoneum

LING Fei-fei, HU Xiao-hong, LI Hong-li, LIU Chang()   

  1. The First School of Clinical Medicine of Lanzhou University, Lanzhou 730000, China (LING Fei-fei, HU Xiao-hong); Department of Obstetrics and Gynecology, The First Hospital of Lanzhou University, Gansu Provincial Clinical Research Center for Gynecological Oncology, Lanzhou 730000, China (LI Hong-li, LIU chang)
  • Received:2025-09-29 Published:2026-04-15 Online:2026-05-08
  • Contact: LIU Chang E-mail:lch@lzu.edu.cn

Abstract:

Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm of mesenchymal origin, and malignant SFT (mSFT) is more aggressive. Occurrence in the pelvic retroperitoneum is exceptionally rare. We report a case of a 55-year-old female who presented with intermittent right lower abdominal pain for over two years, which worsened over the previous week. Imaging revealed a space-occupying lesion in the right adnexal region. The lesion was resected via laparoscopic surgery, and postoperative pathology combined with immunohistochemical findings confirmed mSFT. Based on recent literature, we systematically analyze this case from epidemiological, clinical, imaging, and pathological, differential diagnostic, therapeutic, and prognostic perspectives, aiming to enhance clinicians' ability for early recognition and comprehensive management of pelvic retroperitoneal mSFT.

Key words: Solitary fibrous tumors, Retroperitoneal neoplasms, STAT6 transcription factor, Magnetic resonance imaging, Immunohistochemistry