Journal of International Obstetrics and Gynecology ›› 2024, Vol. 51 ›› Issue (1): 74-77.doi: 10.12280/gjfckx.20230725

• Research on Gynecological Malignancies: Case Report • Previous Articles     Next Articles

Endometrial Metastasis of Lung Adenocarcinoma with Abnormal Vaginal Bleeding as the First Symptom: A Case Report and Literature Review

CHEN Yan-xi, LIU Hui, JIANG Peng-cheng()   

  1. Department of Gynecology, The Afffiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou 213000, Jiangsu Province, China (CHEN Yan-xi, JIANG Peng-cheng); Jiangsu Health Vocational College, Nanjing 210000, China (LIU Hui)
  • Received:2023-09-14 Published:2024-02-15 Online:2024-02-19
  • Contact: JIANG Peng-cheng E-mail:jpc1972@163.com

Abstract:

Primary bronchial lung cancer, commonly known as lung cancer, is one of the malignant tumors with high morbidity and mortality in the world. In recent years, the incidence of lung cancer in women has increased, and most of them are lung adenocarcinoma. Because the early symptoms of lung cancer are occult, it is often detected when metastasis has already occurred. We report a case of endometrial metastasis of lung adenocarcinoma. The patient presented with abnormal vaginal bleeding, and the pathology after curettage indicated adenocarcinoma. After immunohistochemical examination and imaging examination were combined to exclude the possibility of tumor origin in other sites, the diagnosis was confirmed as lung adenocarcinoma metastasis to the endometrium. Metastasis of lung cancer to the endometrium is extremely rare and is likely to be missed or misdiagnosed. In this paper, the data of a case of endometrial metastasis of lung adenocarcinoma were retrospectively analyzed and the relevant literatures were reviewed in order to enhance the clinical vigilance of endometrial metastasis of lung adenocarcinoma.

Key words: Adenocarcinoma of lung, Endometrial neoplasms, Neoplasm metastasis, Diagnosis, Immunohistochemistry, Case reports