Abstract: Objective： To study the ultrasound real-time tissue elastography technique used in the evaluation of cervical maturity during pregnancy. Methods：145 pregnant women were divided into 3 groups according to the gestational weeks. All pregnant women in the routine obstetric ultrasound examination were voluntary to take transvaginal ultrasound cervical evaluation. Cervical length was measured based on two-dimensional ultrasound image，followed by real-time tissue elastography，and then strain rate in the cervical region of interest was gotten during early，mid and late pregnancy. Results：Cervical length and cervical defined region of interest differ at each pregnancy group had statistical significance （P＜0.05）, and the early and mid pregnancy group of cervical length is longer than the third trimester group, cervical defined region of interest differ is less than the late pregnancy group, the difference was statistically significant（P＜0.05）, while there was no statistically significant difference between the early and mid pregnancy group（P＞0.05）. The cervical length was negatively correlation with the strain rate（r=-0.95，P=0.032）. Conclusions：Ultrasound real-time tissue elastography technology during pregnancy plays an important role in cervical maturity evaluation，and it provides accurate index about the cervical maturity. Also, it offers a new examination way to predict premature.

Key words: Ultrasonography, Elasticity imaging techniques, Pregnant women, Cervical