Abstract: Endometrial cancer is one of the most common malignancy of the female reproductive tract, and its incidence is steadily increasing. The lymphatic metastasis is the main route metastasis of endometrial cancer, in which pelvic lymph node metastasis is more common while para-aortic lymph node metastasis is rare. However, patients with para-aortic lymph node metastasis have a relatively poor prognosis. Preoperative and intraoperative techniques could be critical tools for tailoring the para-aortic lymph node metastasis in the endometrial cancer. The prediction methods of the para-aortic lymph nodes metastasis in endometrial carcinoma have been developing rapidly in recent years. But at present, there is still no uniform standard for forecasting techniques. Now we do a review on the comprehensive analysis about patients′ pathological examination, serological examination and imaging modalities to predict the para-aortic lymph node metastasis in the management of endometrial cancer, guide clinical decisions, avoid unnecessary aortic lymphadenectomies, reduce morbidity, lower the cost of surgery and select appropriate postoperative adjuvant therapy, which are all of great significance.

Key words: Endometrial neoplasms, Lymphatic metastasis, Forecasting, Sentinel lymph node biopsy