Journal of International Obstetrics and Gynecology ›› 2018, Vol. 45 ›› Issue (3): 279-282.

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Relationship between Platelet and Their Associated Factors with Endometriosis

WANG Song,SONG Dian-rong   

  1. Tianjin University of Traditional Chinese Medicine, Tianjin 300193,China(WANG Song);Department of Obstetrics and Gynecology,Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300143,China(SONG Dian-rong)
  • Received:2018-01-10 Revised:2018-04-24 Published:2018-06-15 Online:2018-06-22
  • Contact: SONG Dian-rong,E-mail: songdr58@126.com E-mail:songdr58@126.com

Abstract: Endometriosis is a common and frequently encountered disease of gynaecology, it is a kind of chronic benign disease, affecting 10% to 15% of the women of childbearing age, with main symptoms of dysmenorrhea, pelvic adhesions and infertility, but its pathogenesis has not yet known clearly, many of the hypothesis. At home and abroad in recent years, scholars have found that platelets play an important role in the incidence of endometriosis, the main performance of platelet adhesion, aggregation function in patients with endometriosis was flawed, platelet count in patients with endometriosis, its relatively high blood coagulation state, and can be mediated inflammatory response and platelet associated factors such as P-select element, CD40L, platelet growth factors in the pathogenesis of endometriosis have different degrees of promoting function, platelet can affect patients with endometriosis and the expression of estrogen and its receptors, so the review on platelet abnormal function with the pathogenesis of endometriosis may exist, for the clinical application of platelet and provide theoretical basis for treatment of endometriosis.

Key words: Endometriosis, Blood platelets, Blood coagulation, Inflammation, Immunity