Abstract: Objective：To investigate the association of female education level and fertility with their perimenopausal symptoms. Methods: A total of 2 917 perimenopausal patients in the outpatient clinic of gynecology were enrolled in this study. A questionnaire was used to survey basic information. The perimenopausal symptoms were evaluated by revised Kupperman Menopause Index (KMI). Results: The menopausal age is (49.42±3.57) years old in this study. There were statistically significant differences in menopausal age, number of births, number of abortions, number of pregnancies, waist-to-hip ratio, paresthesia, mood swings, depression, suspiciousness, and sexual problems among women of different education levels(all P＜0.05). The total scores of revised Kupperman Menopause Index were also significantly different among different education levels, the number of births and the number of pregnancies (all P＜0.05). Conclusions: The lower the education levels, the more times of the birth and pregnancy, and the higher of the revised Kupperman scores, than the more severe the perimenopausal symptoms. The clinical treatment of perimenopausal women with different education level and fertility status should be individualized.

Key words: Culture, Reproductive history, Climacteric syndrome, Questionnaires