Relationship between Psychological Pressure in Early Pregnancy Period and Spontaneous Abortion

doi:10.12280/gjfckx.20220959

Abstract

Abstract:

Objective: To investigate the relationship between psychological pressure and spontaneous abortion in pregnant women in early pregnancy. Methods: Patients with early pregnancy in Fu Xing Hospital affiliated to Capital Medical University from June 2019 to August 2021 were enrolled. The "early pregnancy women psychological health survey" questionnaire was used, follow up until 12 weeks of pregnancy, and 108 cases of spontaneous abortion were selected as the observation group and 202 cases of normal early pregnancy were selected as the control group. The risk factors related to psychological stress of spontaneous abortion during early pregnancy and the moderating effect of emotion regulation strategy on perceived stress and spontaneous abortion were analyzed. Results: The scores of perceived stress and stress sources during pregnancy in the observation group were significantly higher than those in the control group (P<0.01). Multi-factor logistic regression analysis showed that concern about the health of offspring (OR=1.188, 95%CI: 1.006-1.402, P=0.042), number of previous spontaneous abortion (OR=2.740, 95%CI: 1.117-6.722, P=0.028) and perceived stress (OR=1.194, 95%CI: 1.134-1.257, P<0.001) were risk factors of spontaneous abortion. Emotion regulation strategy moderated the relationship between perceived stress and spontaneous abortion. Cognitive reappraisal multiplied by perceived stress was significantly negatively correlated with spontaneous abortion (B=-0.067, OR=0.935, 95%CI: 0.915-0.957, P<0.001), while expressive suppression multiplied by perceived stress was significantly positively correlated with spontaneous abortion (B=0.004, OR=1.004, 95%CI: 1.001-1.007, P=0.010). Conclusions: High psychological stress level during pregnancy is a risk factor for spontaneous abortion, and the psychological stress mainly comes from the number of previous spontaneous abortion. Under high level of perceived stress, the frequent use of cognitive reappraisal and reducing the use of expressive suppression can reduce the occurrence of spontaneous abortion.

Key words: Abortion, spontaneous, Pregnancy trimester, first, Pregnant women, Risk factors, Questionnaires

YAN Jing, LI Xiao-yu, ZHANG Jing. Relationship between Psychological Pressure in Early Pregnancy Period and Spontaneous Abortion[J]. Journal of International Obstetrics and Gynecology, 2023, 50(3): 349-353.

Figures/Tables 4

References 26

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组别	n	年龄（岁）	孕周（周）	家庭人口			人均月收入			职业			受教育程度
组别	n	年龄（岁）	孕周（周）	≤2人	3~4人	≥5人	≤5 000元	5 001~8 000元	>8 000元	体力劳动	脑力劳动	两者兼有	初级	中级	高级
观察组	108	32.06±4.03	7.71±2.07	55（50.93）	44（40.74）	9（8.33）	11（10.19）	17（15.74）	80（74.07）	5（4.63）	56（51.85）	47（43.52）	3（2.78）	5（4.63）	100（92.59）
对照组	202	31.47±3.75	7.39±1.59	128（63.37）	58（28.71）	16（7.92）	11（5.45）	36（17.82）	155（76.73）	3（1.49）	109（53.96）	90（44.55）	2（0.99）	7（3.47）	193（95.54）
t或χ²		-1.286	-1.410	3.320			1.844			2.711			1.543
P		0.199	0.160	0.190			0.398			0.258			0.462

组别	n	年龄（岁）	孕周（周）	家庭人口			人均月收入			职业			受教育程度
组别	n	年龄（岁）	孕周（周）	≤2人	3~4人	≥5人	≤5 000元	5 001~8 000元	>8 000元	体力劳动	脑力劳动	两者兼有	初级	中级	高级
观察组	108	32.06±4.03	7.71±2.07	55（50.93）	44（40.74）	9（8.33）	11（10.19）	17（15.74）	80（74.07）	5（4.63）	56（51.85）	47（43.52）	3（2.78）	5（4.63）	100（92.59）
对照组	202	31.47±3.75	7.39±1.59	128（63.37）	58（28.71）	16（7.92）	11（5.45）	36（17.82）	155（76.73）	3（1.49）	109（53.96）	90（44.55）	2（0.99）	7（3.47）	193（95.54）
t或χ²		-1.286	-1.410	3.320			1.844			2.711			1.543
P		0.199	0.160	0.190			0.398			0.258			0.462

组别	n	知觉压力	孕期症状	担心子代健康	父母角色认同	社会关系	工作压力	家庭关系
观察组	108	23.71±5.64	12.63±3.94	7.56±3.36	8.19±3.77	18.24±7.92	13.59±5.65	9.83±4.22
对照组	202	16.43±7.20	10.17±2.73	5.51±1.66	6.25±1.87	13.28±3.96	10.03±3.15	7.70±1.90
t		-9.806	-5.781	-5.954	-5.025	-6.119	-6.072	-4.978
P		<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001

组别	n	知觉压力	孕期症状	担心子代健康	父母角色认同	社会关系	工作压力	家庭关系
观察组	108	23.71±5.64	12.63±3.94	7.56±3.36	8.19±3.77	18.24±7.92	13.59±5.65	9.83±4.22
对照组	202	16.43±7.20	10.17±2.73	5.51±1.66	6.25±1.87	13.28±3.96	10.03±3.15	7.70±1.90
t		-9.806	-5.781	-5.954	-5.025	-6.119	-6.072	-4.978
P		<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001

变量	B	SE	Wald χ²	P	OR（95%CI）
知觉压力	0.177	0.026	45.393	0.001	1.194（1.134~1.257）
既往自然流产次数	1.008	0.458	4.844	0.028	2.740（1.117~6.722）
孕期症状	0.081	0.060	1.794	0.180	1.084（0.963~1.220）
担心子代健康	0.172	0.085	4.143	0.042	1.188（1.006~1.402）
父母角色认同	0.043	0.078	0.313	0.576	1.044（0.897~1.216）
社会关系	0.072	0.050	2.112	0.146	1.075（0.975~1.185）
工作压力	-0.017	0.067	0.062	0.804	0.984（0.863~1.121）
家庭关系	0.070	0.082	0.722	0.395	1.072（0.913~1.259）