Abstract:

In the peripartum period, euthyroidism is essential for maternal-fetal health. More and more studies have found that thyroid diseases may lead to female infertility, increase the risk of pregnancy-related complications such as gestational hypertension, thyroid crisis, spontaneous abortion, preterm birth, and stillbirth, and may impair the neurological and intellectual development of offspring. The diagnostic criteria of thyroid diseases during pregnancy are different from those of non-pregnant women due to the unique physiological changes of thyroid in this special period. Moreover, the symptoms and signs of perinatal thyroid diseases often overlap with the physiological manifestations of pregnancy, which increases the difficulty of clinical diagnosis. Thyroid diseases are common endocrine disease in the peripartum period, and its situation is complex, its diagnostic and treatment strategies should consider the safety of both mothers and infants. Relevant updated guidelines have been issued by domestic and foreign professional societies, which provided detailed suggestions regarding clinical managements of thyroid diseases during peripartum period. This review combined with the latest research evidence comparatively analyzes and interprets the main points of diagnosis and treatment of the recent guidelines at home and abroad, in order to provide references for clinicians regarding the diagnosis and treatment of perinatal thyroid diseases.

Key words: Peripartum period, Pregnant women, Thyroid diseases, Diagnostic and treatment guideline, Pregnancy outcome