Abstract: Objective：To investigate the clinical recurrence risk factors after laparoscopic adenomyoectomy. Methods：From Jan. 2010 to Jan. 2015, 109 patients undering laparoscopic adenomyomectomy were recruited in Gynecologic Minimally Invasive Center of Beijing Obstetrics and Gynecology Hospital Affiliated to Capital Medical University were recruited. The patients demographic, clinic characteristics, preoperative and postoperative information was reviewed and analyzed. Gonadotropin-releasing hormone agonist (GnRHa) therapy, surgical approach, follow-up information was also collected. Results：The culmulative rate of 12, 24 and 36 months after operation was 14.9%, 22.7% and 25.7% respectively. Age had a significant effect on postoperative recurrence rate. With the age increasing，the risk of relapse decreased 10% (RR=0.900, 95%CI: 0.822-0.986, P=0.023). The preoperative uterine volume was the risk factor of postoperative recurrence (RR=1.289, 95%CI: 1.121-1.678, P=0.005). Postoperative GnRHa therapy was a protective factor for postoperative recurrence (RR=0.407, 95%CI: 0.185-0.895, P=0.025). The patient′s pregnancy history, the preoperative dysmenorrhea score, the maximum size of the adenoma, the position of the adenoma, preoperative GnRHa therapy, surgical approach and endometriosis were not risk factors for postoperative recurrence rate. Conclusions：The age, preoperative uterine volume and no postoperative GnRHa therapy are the risk factors for recurrence after laparoscopic hysterectomy.

Key words: Adenomyosis, Recurrence, Risk factors, Laparoscopes